Metformin and Fertility

What connection do Metformin and fertility have? Metformin can actually help with fertility issues.
First you must understand what it is and what it actually does.

What is Metformin?

Developed in 1957 its main purpose is to help suppress the production of endogenous glucose by the liver.

Other names for Metformin:


Fortamet
Glucophage
Glucophage XR
Glumetza
Riomet

What does it do?

The main purpose is to suppress the production of endogenous glucose by the liver. It does not cause you to become hypoglycemic, gain weight or increase insulin secretion like other medications for diabetes does. Basically it helps to keep insulin effective without changing the level of insulin in the body.

Among the uses of Metformin and fertility it has been shown to have a use in settling infertility issues. It has been shown that the female reproductive system requires insulin for proper functioning. If there is too much insulin present in the body the ovaries may not do what they are supposed to do so there is a direct link with insulin and pregnancy. PCOS (Polycystic Ovarian Syndrome) causes infertility. Women with this syndrome have small cysts on the ovaries and do not experience normal ovulation or regular menstrual cycles.

There are those that have attempted to treat PCOS with clopimheme or Clomid which induces ovulation. Recently Metformin has been used both with and without it to help women with PCOS ovulate. It helps the body to manage and respond to insulin which helps the ovaries to function better. This helps to develop a more regular ovulation cycle.

It has also been found that there is the possibility of miscarriages and to cut down on the risk of gestational diabetes. A delay or prevention of Type 2 diabetes is also believed to be associated with it.

SIDE EFFECTS OF METFORMIN:

  • Abdominal pain or cramping
  • Discomfort
  • Nausea
  • Vomiting- this is when you should top taking Metformin.
  • Diarrhea

Interactions should be watched for with steroids, diuretics, nicotinic acid and some forms of birth control that is taken orally.

Note* Metformin may interfere with Vitamin B12 absorption. Your doctor can tell you about vitamin supplements and or changes in diet that should come with the use of this medication.

A condition known as lactic acidosis is a dangerous condition that one out of thirty-three thousand women develop when taking Metformin. This is most common in those with reduced functioning of the kidneys or liver and those that become dehydrated while they are taking this medication. Testing of the kidney and liver function is tested though blood test before therapy involving Metformin and fertility begins.

Metformin and fertility should not be addressed together by someone under lots of physical stress such as those with a severe illness, who are recovering from a severe trauma or have just had surgery. You have to be sure to stay hydrated while taking this medication. Alcohol is not recommended when trying to conceive and should not be taken with Metformin at all. Stop taking metformin two days prior to having a surgical procedure performed.